We adopt the most suitable carriers and strategies for your application

Immobilizing an enzyme can improve the performance of your process

BiCT offers you its expertise in the field of enzyme immobilization, adopting the most suitable carriers and strategies for the required application (adsorption, covalent bonding, or modifications in the functionalities). It is possible to apply the technology both to newly designed enzymes and to commercial enzymes.

We immobilize commercial or proprietary enzymes

We take care of immobilizing one or more commercial enzymes currently in use in your processes in free form or a specific enzyme of your own.

If the enzyme of your interest is not commercially available and needs to be developed, Bict can provide it to you: with expertise in the field of mutagenesis, heterologous protein expression and subsequent purification, we can produce it for feasibility studies and/or for subsequent industrial scale-up.

With expertise in both biotechnology and chemistry, we can develop and optimize enzyme-mediated or multistep biocatalysis processes with chemo-enzymatic steps. Enzymes can be used either free or immobilized, based on application and convenience.

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    Development of innovative industrial processes enzymatic and chemo-enzymaticFermentation developmentEnzyme immobilizationDownstream DevelopmentStrain developmentBioconversion developmentHeterologous expressionMutagenesis and evolution of strains and enzymesAnalytical method developmentALLOTHER

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    What are the benefits to using immobilized enzymes industrially?

    • It lowers the supply costs of biocatalysts, due to the possible reuse of the enzyme.
    • In some fields, such as food, it allows not to have the residual enzyme inside the product.
    • It allows the use of the enzyme also in the presence of solvents, as it is in solid non-aqueous phase.
    • It improves the stability of the catalyst.
    • It confers particular reaction characteristics or modify the kinetic parameters of the biocatalyst.

    To obtain these advantages, Bict offers a service of industrial biocatalysis development, using commercial or proprietary enzymes, depending on the convenience, also thanks to targeted screening by automated scale-down.

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    Development of innovative industrial processes enzymatic and chemo-enzymatic
    Fermentation development
    Enzyme immobilization
    Downstream Development
    Strain development
    Bioconversion development
    Heterologous expression
    Mutagenesis and evolution of strains and enzymes
    Analytical method development